运动干预对患癌症儿童癌症相关疲劳的影响:元分析
Siyu Wang1, Mengqiao Li1, Yuchen Wu1
1School of Nursing and Health, Zhengzhou University, Zhengzhou, China.
Worldviews on evidence-based nursing
|September 29, 2024
概括
运动干预有效地减少癌症相关疲劳 (CRF) 在接受癌症治疗的儿童. 每周3次以上的炼,每次不到45分钟,持续时间小于12周的炼,可以获得最佳效果.
科学领域:
- 儿科瘤学 儿科瘤学
- 康复医学 康复医学 康复医学
- 临床运动生理学 临床运动生理学
背景情况:
- 与癌症相关的疲劳 (CRF) 是儿童癌症患者在治疗期间经历的一种普遍和衰弱的症状.
- 运动干预越来越被认为是减轻该脆弱人群中CRF的可行策略.
研究的目的:
- 进行一项元分析,综合现有的关于运动干预措施在癌症儿童中治疗CRF有效性的证据.
- 为优化运动方案提供基于证据的建议,以改善儿童癌症患者的CRF.
主要方法:
- 从开始到2023年12月,对六个数据库进行了系统搜索,以确定相关的随机对照试验.
- 使用柯克伦评估工具来评估所包含的研究的偏差风险和方法质量.
- 随机效应模型用于聚合效应计算,使用I平方 (I2) 测试评估异质性.
主要成果:
- 八个随机对照试验涉及465名参与者被纳入了元分析.
- 与传统护理相比,运动干预表明CRF在统计学上有显著的改善 (SMD = -0.62,95%CI [-1.21, -0.03]).
- 观察到很高的统计异质性 (p = .004;I2 = 86%),表明研究结果的变化. 亚组分析显示,持续时间<12周,频率≥3次/周,持续时间<45分钟/会议的干预措施是最有效的.
结论:
- 运动干预措施有效地减少了儿童癌症患者的癌症相关疲劳.
- 特定的运动参数,包括频率 (每周≥3次),会话持续时间 (<45分钟) 和整体干预持续时间 (<12周),与CRF的更大改善有关.
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