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使用血管化的粘膜片与外部皮肤复杂组织复杂组织重建广泛的下唇缺陷
Haosen Lian1, Yufei Hua1, Grace Paka Lubamba2
1State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Head and Neck Oncology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Oral oncology
|September 29, 2024
概括
在癌症手术后重建下唇缺陷是复杂的. 一个面部动脉肌岛 (FAMMIF) 与外部皮肤组织有效地恢复了美学和功能,从而使患者满意.
科学领域:
- 口腔和牙面部外科手术
- 整形和重建手术 整形和重建手术
- 在瘤学瘤学.
背景情况:
- 唇部重建由于复杂的解剖学和功能而存在挑战.
- 适当的修复需要恢复粘膜,红和皮肤特征.
研究的目的:
- 评估面部动脉肌岛片 (FAMMIF) 与外皮复合组织用于下唇重建的疗效.
- 评估这种重建技术的综合美学和功能成果.
主要方法:
- 一名患有下唇癌的59岁男性接受了切除和部剖析.
- 立即进行重建,使用仿真:FAMMIF与外部皮肤组织相结合.
主要成果:
- 结合式片最大限度地减少了术后的美学和功能障碍.
- FAMMIF重建了唇膜和红;外部皮肤组织取代了唇皮.
- 患者表示对治疗结果感到满意,并在随访期间没有出现复发.
结论:
- 使用外皮复杂组织的FAMMIF是一种可行的技术,用于癌症后切除唇部缺陷.
- 这种方法成功地重建了下唇的美学和功能.
- 取得了令人满意的术后结果.
相关概念视频
Overview of Regeneration and Repair
Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...
Regeneration
All animals have varying degrees of...
Phases of Wound Repair
Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Clot Retraction and Fibrinolysis
After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.
Healing II: Complications
Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...

