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Updated: Jun 11, 2025

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介素-38在慢性结肠炎中调节T细胞中的作用:小鼠模型研究

Ying Xu1, Xuan Zhang2, Shanshan Liu2

  • 1Office of Drug Clinical Trials, Affiliated Hospital of Guilin Medical University, Guilin 541001, Guangxi, China.

Cytokine
|September 29, 2024
PubMed
概括

干白素-38 (IL-38) 通过增强调节性T细胞 (Tregs) 和减少炎症性Th1/Th17和γδT细胞来缓解小鼠慢性结肠炎. 这表明IL-38是IL-38.

关键词:
慢性结肠炎是一种慢性结肠炎.德克斯特兰硫酸盐和它们的IL-38是IL-38.监管T细胞监管T细胞一个Th1细胞.Th17细胞的细胞.γδ T 细胞的 T 细胞

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T Cell Types and Functions01:24

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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