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Updated: Jun 11, 2025

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在败血症中以生理学为基础的药理动力学建模:阐明病理生理学如何影响美罗的药理动力学的工具

Salma M Bahnasawy1, Neil J Parrott2, Matthias Gijsen3

  • 1Department of Pharmacy, Uppsala University, Uppsala, Sweden.

International journal of antimicrobial agents
|September 29, 2024
PubMed
概括

基于生理学上的药理动力学 (PBPK) 建模准确地预测了败血症患者的美洛暴露. 这种方法增强了对败血症如何影响药物药理动学的理解,有助于优化剂量策略.

关键词:
梅罗佩内姆 (Meropenem) 是一种美的成分.PBPKK PBPK 的意思是什么意思败血症 这是一种败血症.

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