管的大小是否会改变氨酸填充剂的风湿性质?
Andrea Lisboa Sisnando1, Vasudev Vivekanand Nayak2, Mariana Barbosa Câmara-Sousa1
1Ingá University Center, Uningá, Paraná, Brazil.
International journal of biological macromolecules
|September 29, 2024
概括
通过22-G和25-G穿过氨酸 (HA) 填充剂并没有改变它们的质性质. 这些高交联HA凝保持了它们的固体状,体积增大行为,对于面部应用至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 材料科学 材料科学 材料科学
- 生物医学工程 生物医学工程
背景情况:
- 氨酸 (HA) 填充剂广泛用于面部体积化.
- 了解注射后的填充剂行为对于可预测的美学结果至关重要.
- 管的大小可能会影响HA填充剂的风湿性质.
研究的目的:
- 评估管通道对交联HA填充剂的风湿性质的影响.
- 为了确定管大小是否会影响美学程序中使用的HA填充剂的性能.
主要方法:
- 分析了5种商用高交联HA填充剂.
- 在穿过22-G和25-G小之前和之后,测量了rheological属性 (G'和G").
- 采用自动控制应力类风湿测量,频率为0.1,0.5和2赫兹.
主要成果:
- 在填充剂通过管后,没有观察到存储模量 (G) 或损失模量 (G) 的显著变化.
- 所有经过测试的HA填充剂在低频率和应变幅度下都表现出理想的固体状体积增大特性.
- 在测试条件下,管大小没有改变高交叉链接HA填充剂的风湿学特征.
结论:
- 管的大小不会影响高交联HA填充剂的质完整性.
- HA填充剂保持其预期的体积和结构性质,无论用于注射的管大小如何.
- 这些发现支持HA填充剂在临床面部应用中的一致性.
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