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相关概念视频

Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

65
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
65
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

451
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
451
Dementia01:30

Dementia

99
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
99
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists01:30

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

106
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
106
Intellectual Disability01:29

Intellectual Disability

44
Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
44

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Longitudinal cognitive outcomes in two progressive supranuclear palsy clinical trials.

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相关实验视频

Updated: Jun 11, 2025

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

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轻度认知障碍:量化一种定性障碍

Kevin Duff1

  • 1Department of Neurology, Layton Aging & Alzheimer's Disease Research Center, Oregon Health & Science University, 3181 Southwest Sam Jackson Park Road (Mail code: CR131), Portland, OR 97239, USA.

Neurologic clinics
|September 29, 2024
PubMed
概括

轻度认知障碍 (MCI) 是正常衰老和痴呆之间的过渡阶段. 定量方法提供了一种跟踪认知变化的方法,并评估对这种疾病的干预措施.

科学领域:

  • 神经学 神经学
  • 老年学是一门学科.
  • 认知科学 认知科学

背景情况:

  • 轻度认知障碍 (MCI) 是正常认知衰老和痴呆症之间的关键过渡阶段.
  • MCI的特点是主观的认知投诉,客观的认知缺陷和保存的日常功能.

研究的目的:

  • 探索定量方法在识别和跟踪轻度认知障碍方面的作用.
  • 评估量化方法在评估MCI患者干预措施中的潜力.

主要方法:

  • 使用定性和定量视角来识别和监测MCI.
  • 应用客观认知评估来追踪随时间的微妙变化.

主要成果:

  • 常见的是MCI进展为痴呆症,但也观察到稳定性和恢复正常认知.
  • 定量方法为评估MCI中微妙的认知下降提供了一种手段.

结论:

  • 量化方法是医疗保健提供者在管理和研究轻度认知障碍方面有价值的工具.
  • 这些方法可以帮助评估旨在缓解MCI进展的干预措施的有效性.
关键词:
认知障碍 认知障碍 认知障碍轻度认知障碍 轻度认知障碍神经心理学 神经心理学心理测量 心理测量 心理测量

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