怀孕中的COVID-19:在一个大型卫生系统中的流行率,管理和结果
Anna Schulte1, Sandra Castro-Pearson2, Abbey Sidebottom1
1Care Delivery Research, Allina Health, Minneapolis, MN, USA.
概括
患有SARS-CoV-2 (严重急性呼吸系统综合征冠状病毒2) 的孕妇患者大多没有症状. 怀孕期间出现症状的COVID-19病例增加了住院治疗和不良周产期结果.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 怀孕期间SARS-CoV-2感染的患病率和影响需要持续评估.
- 了解COVID-19对孕产妇和围产期结果的影响对于临床管理至关重要.
研究的目的:
- 为了确定在孕妇患者中SARS-CoV-2阳性的患病率.
- 根据SARS-CoV-2状态和COVID-19症状学来比较孕产妇和产后结果.
主要方法:
- 从2020年3月到2021年12月,对24,310例怀孕的回顾性队列研究.
- 在怀孕期间通过阳性测试或COVID-19诊断定义的SARS-CoV-2阳性.
- 在负面,无症状的阳性和症状的阳性SARS-CoV-2组之间比较结果.
主要成果:
- 1.5%的怀孕有COVID-19的症状,3.9%的无症状阳性,和94.6%的阴性.
- 症状患者住院率 (16.8%) 和ICU入院率 (13.0%) 较高.
- 与无症状 (9.5%) 或负 (9.8%) 组相比,有症状的患者 (15.7%) 的早产率显著更高.
结论:
- 大多数感染SARS-CoV-2的孕妇患者无症状.
- 怀孕期间出现症状的COVID-19显著增加了住院和ICU入院的需要.
- 不良周产期结果,包括早产,在有症状的SARS-CoV-2阳性孕妇中更为频繁.
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