相关实验视频
Updated: Jun 11, 2025

07:36
High-Throughput Analysis of Optical Mapping Data Using ElectroMap
Published on: June 4, 2019
9.3K
详细分析电图的峰值频率,以指导心室动脉冲动脉基质映射
Joseph Mayer1,2, Jaffar Al-Sheikhli1,3, Maria Niespialowska-Steuden1
1Department of Cardiology, University Hospital Coventry and Warwickshire NHS Trust, CV2 2DX Coventry, UK.
概括
低压区域的峰值频率映射有效地识别了心室动脉冲动回路的关键组件. 一个≥200Hz的最佳值有助于静脉瘤切除成功.
科学领域:
- 电力生理学 电力生理学
- 心脏节律失常症 心脏节律失常症
- 信号处理 信号处理
背景情况:
- 区分近场 (NF) 和远场 (FF) 电图 (EGM) 对于在心室动脉冲动 (VT) 移除过程中识别关键心律失常基质至关重要.
- 新的算法可以注释NF分片信号,并使用波波变换来确定EGM峰值频率 (PF).
研究的目的:
- 评估一种新的算法在基质映射过程中识别VT电路的关键组件的有效性.
- 为了评估低压区域 (LVA) PF基底映射用于静脉瘤切除的诊断性能.
主要方法:
- 研究了一个多中心的国际队列,接受了静脉瘤切除,使用静脉瘤激活地图划分峡谷区域 (IZ).
- 进行离线分析以评估LVA PF基质映射诊断性能.
- 包括30名患者和198935名EGM,分析PF在鼻节律 (SR) 和右心室节奏 (RVp) 条件下.
主要成果:
- 与RVP基底图相比,在SR中 Isthmus zone (IZ) 的PF显著高于RVP基底图 (234 Hz与197 Hz相比;P = 0.010).
- 在SR和RVP图表中,IZ PF显著高于LVA PF (AUC分别为0.74和0.70).
- 在SR和RVP地图中,LVA PF值≥200 Hz是确定静脉脉峡的最佳值 (灵敏度为60-69%;特异性为64%).
- 在接受阿米奥达龙治疗的患者中,相对于未接受阿米奥达龙治疗的患者 (222 Hz与303 Hz相比;P = 0.009),SR基质图IZ PF显著较低.
- 低于200Hz的LVA PF值与80%的静脉瘤无关,并趋向于减少切除病变和射频时间.
结论:
- 低压区域 (LVA) PF基板映射有效地识别了VT电路的关键组件,其最佳值为≥200 Hz.
- Isthmus PF受慢性阿米奥达龙治疗的影响,并且在RV节奏时较低.
- 这种映射方法显示了改善VT切除结果的前景.
相关概念视频
Electrocardiogram
2.2K
An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
2.2K
Dysrhythmias III: Characteristics of Dysrhythmias
3
Dysrhythmias, also known as arrhythmias, are irregular heart rhythms that result from abnormal electrical activity in the heart, affecting its ability to circulate blood efficiently. Tachyarrhythmias, a subset of dysrhythmias, are characterized by abnormally fast heart rates exceeding 100 beats per minute. Here are some types of tachyarrhythmias with their distinct ECG features:Sinus Tachycardia:Sinus tachycardia presents a regular heart rhythm with an increased rate of 101-180 beats per...
3
Electrocardiogram Fundamentals
542
Introduction
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
542
ECG Interpretation of Rhythms
544
An electrocardiogram (ECG)graphically represents the heart's electrical activity on ECG paper or a monitor.
Components of the Electrocardiogram
The primary components of a normal ECG waveform in Normal sinus rhythm(NSR) include the P wave, PR interval, QRS complex, ST segment, T wave, and occasionally a U wave.
ECG waveforms are divided by vertical and horizontal lines at standard intervals.
The horizontal axis measures time and rate, and the vertical axis measures amplitude or voltage....
Components of the Electrocardiogram
The primary components of a normal ECG waveform in Normal sinus rhythm(NSR) include the P wave, PR interval, QRS complex, ST segment, T wave, and occasionally a U wave.
ECG waveforms are divided by vertical and horizontal lines at standard intervals.
The horizontal axis measures time and rate, and the vertical axis measures amplitude or voltage....
544
Cardiac Action Potential
1.1K
Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
1.1K
Electrophysiology of Normal Cardiac Rhythm
2.3K
The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase...
2.3K

