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Updated: Jun 14, 2025

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RAB12-LRRK2复合物抑制了初级纤维生成,并调节了星球细胞中中心体恒常性

Xingjian Li1,2, Hanwen Zhu3,4, Bik Tzu Huang1,5,6

  • 1Department of Neurology, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Nature communications
|September 29, 2024
PubMed
概括

帕金森病 (PD) 研究人员发现,RAB12和LRRK2蛋白相互作用抑制了纤维生成和中心体恒常. 这一发现通过调节这种RAB12-LRRK2相互作用,为PD提供了新的治疗点.

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