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Updated: Jun 11, 2025

Multimer-PAGE: A Method for Capturing and Resolving Protein Complexes in Biological Samples
07:40

Multimer-PAGE: A Method for Capturing and Resolving Protein Complexes in Biological Samples

Published on: May 5, 2017

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从蛋白质结构到使用多尺度建模的优化色谱捕获步骤

Daphne Keulen1, Tim Neijenhuis1, Adamantia Lazopoulou1

  • 1Department of Biotechnology, Delft University of Technology, Delft, The Netherlands.

Biotechnology progress
|September 30, 2024
PubMed
概括

这项研究整合了定量结构-属性关系 (QSPR) 和机械建模 (MM) 以优化生物制药酸交换 (CEX) 染色学. 这种in silico方法显著减少了用于高效的工艺开发的实验力度.

关键词:
生物制药下游加工 生物制药下游加工染色体学 染色体学 染色体学机械模型模型机械模型过程优化优化过程优化定量结构 财产关系

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