丸激素的回顾:雌激醇比率 - - 它是否重要,你如何测量它,你可以优化它吗?
Arthur L M Swislocki1,2, Michael L Eisenberg3
1Medical Service, VA Northern California Health Care System, Martinez, CA, USA.
The world journal of men's health
|September 30, 2024
概括
:雌激醇比对男性健康至关重要,潜在的有益范围为10-30. 需要进一步的研究来确定最佳水平和测量策略.
科学领域:
- 内分泌学 在内分泌学.
- 男人的健康 男人健康
- 生殖生物学 生殖生物学
背景情况:
- 和雌激醇之间的平衡至关重要,受到自然过程和激素疗法的日益使用的影响.
- 外源性和非标签性芳酶使用会影响这种微妙的荷尔蒙平衡,特别是在男性健康环境中.
- 了解:雌激醇比率是管理荷尔蒙健康和潜在的催产素效应的关键.
研究的目的:
- 审查关于男性丸激素:雌激醇比率的现有数据,考虑自然变异和药理学操纵.
- 探索改变:雌激素比率的临床影响,包括对精子生成,骨密度和甲状腺功能的影响.
- 突出当前测量技术的局限性以及对标准化协议和规范性数据的需求.
主要方法:
- 对报告丸激素:雌二醇比率的研究的文献综述.
- 分析自然存在的和药理上操纵的比例.
- 考虑测量技术,样品时间和试验变异性.
主要成果:
- 一个潜在的有益的:雌激醇比率范围为10-30 (在ng/dL /雌激醇在pg/mL) 是建议的.
- 较高的比率可能与改善的精子生成和骨密度降低相关.
- 较低的比率与甲状腺功能障碍有关,表明这种比率具有广泛的影响.
结论:
- 虽然人们对:雌激醇比重的重要性的认识越来越大,但最佳范围尚未确定.
- 测量准确度和标准化方面的重大限制阻碍了对比率的精确解释.
- 进一步的研究是必不可少的,以完善测量策略,并确定清晰的测量结果测量:雌激醇比率.
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