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Updated: Jun 30, 2026

Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope
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独特的免疫特征是由desmuramylpeptide NOD2激活剂的结构变化所驱动的

Špela Janež1, Samo Guzelj1, Petra Kocbek1

  • 1Faculty of Pharmacy, University of Ljubljana, SI-1000 Ljubljana, Slovenia.

Journal of medicinal chemistry
|September 30, 2024
PubMed
概括

研究人员设计了针对核酸结合寡聚化域含有蛋白2 (NOD2) 的新型德斯穆拉密胺激动剂. 化合物3在体外表现出强大的NOD2激素,而其他化合物则表现出独特的免疫调节作用,包括抗炎和疫苗辅助剂的潜力.

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