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Updated: Jun 11, 2025

Induction and Testing of Hypoxia in Cell Culture
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低氧诱导的TIMAP在内皮细胞中的上调和TIMAP依赖的瘤血管生成

Salah Aburahess1, Laiji Li1, Aashiq Hussain1

  • 1Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.

American journal of physiology. Cell physiology
|September 30, 2024
PubMed
概括

抑制TGFβ的膜相关蛋白 (TIMAP) 促进血管生长. 缺氧和生长因子会增加TIMAP,而BMP9会降低TIMAP,影响瘤生长. 在小鼠中,TIMAP缺乏会减少瘤血管生成和生长.

关键词:
在ALK1中,ALK1是ALK1.BMP9 BMP9 BMP9 BMP9 BMP9 BMP9 BMP9 BMP9 BMP9 BMP9 BMP9 BMP9 BMP9这就是HIF-α.乳腺癌 乳腺癌 乳腺癌细胞内皮的内皮.

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