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Updated: Jun 11, 2025

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
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[通过第三代测序对新型HLA-DPB1*02:01:69等位基因进行序列分析和鉴定]

Yizhen He1, Nanying Chen, Shuoxian Zhao

  • 1Blood Center of Zhejiang Province, Hangzhou, Zhejiang 310052, China. zfm00@hotmail.com.

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
|September 30, 2024
PubMed
概括

研究人员使用下一代测序 (NGS) 和第三代测序 (TGS) 确定了一种新的人类白细胞抗原 (HLA) DPB1*02:01:69等位基因. 这种新型的HLA DPB1等位基因在献血者样本中被发现.

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Genome-wide Association Studies-GWAS01:11

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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