相关实验视频

Updated: Jun 11, 2025

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy
08:40

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy

Published on: August 1, 2013

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针对树突细胞的纳米粒子通过促进抗原呈现和阻断PD-L1通路来增强T细胞激活和抗瘤免疫反应

Prateek Srivastava1, Marie Rütter1, Gover Antoniraj1

  • 1Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.

ACS applied materials & interfaces
|September 30, 2024
PubMed
概括

这项研究开发了新型纳米颗粒来增强树突细胞 (DC) 抗原呈现和阻断抑制PD-L1相互作用,显著提高T细胞介导的抗瘤反应对黑色素瘤. 纳米粒子策略为当前的抗PD-L1免疫疗法提供了一个有希望的替代方案.

关键词:
在PD-L1中.在T细胞,T细胞.抗原呈现的呈现方式.抗瘤免疫力 免疫力克洛特里马佐尔 (clotrimazole) 是一种药物.树突细胞是一种树突细胞.半孔的二氧化纳米粒子.瘤微环境是一个微环境.

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