Axin1通过抑制Hertwig的上皮根盖中的AKT1-mTORC1激活和Shh翻译来调节牙根的发育

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Xiaoyu Zheng1,2, Hongcan Huang1,2, Zhipeng Zhou3

  • 1State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, Hubei 430079, China.

Development (Cambridge, England)
|September 30, 2024
PubMed
概括

赫特维格上皮根盖 (HERS) 中的axin1对于牙根的发育至关重要. 它的缺失会通过AKT1-mTORC1途径扰乱核糖体生物发生和mRNA翻译,导致根缺陷.

关键词:
在Axin1中使用了Axin1的方法.赫特维格的上皮细胞根盖.蛋白质合成 蛋白质合成核糖体 核糖体 核糖体 核糖体牙根的发育 牙根的发育

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