临床试验中的噪音或音乐暴露:对伦理和方法学考虑的广泛审查
Eleftheria Iliadou1,2, Vasileios Bitzios1, Konstantinos Pastiadis3
1First Department of Otorhinolaryngology and Head and Neck Surgery, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Noise & health
|September 30, 2024
概括
实验性大噪声和音乐研究可以导致暂时的听力变化,但通常不会造成持久的伤害. 研究人员应考虑伦理和方法方面的因素,以期研究噪音暴露的影响.
科学领域:
- 听力学 听力学是指听力学.
- 实验心理学 实验心理学
- 职业健康 职业健康 职业健康
背景情况:
- 在噪音/音乐研究中,平衡参与者安全与可测量的结果的需求至关重要.
- 在设计涉及大声听觉刺激的实验时,道德和方法方面的考虑至关重要.
- 本综述综合了人类研究中对大噪声/音乐暴露的现有研究.
研究的目的:
- 总结实验性大声噪音/音乐研究的伦理和方法方面.
- 审查使用大噪声/音乐暴露的研究报告的结果.
- 为未来涉及听觉刺激的实验范式的设计提供信息.
主要方法:
- 搜索了四个数据库 (Medline,Central,Web of Science,Scopus) 和两个试验注册表.
- 提取了研究设计,人口,材料,测试和结果的数据.
- 包括34项研究,调查大噪声或音乐对参与者的影响.
主要成果:
- 十一项研究使用噪音 (高达115dBA),十项研究使用音乐 (高达106dBA).
- 观察到暂时的值转移 (TTS) 和减少的耳声排放,大多数参与者听力完全恢复.
- 非听力研究报告了暂时的压力和心血管变化,噪音可能会加剧耳声并影响高血压患者.
结论:
- 实验性大声噪音/音乐暴露可以引起暂时的听力改变,没有显著的长期健康影响.
- 确定方法和伦理方面的考虑对于未来的研究设计至关重要.
- 未来的研究应该优先考虑参与者的安全,同时实现可测量的实验结果.
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