通过客观营养指数和预测因素对COVID-19住院患者的营养不良的评估
Lingmei Zhou1, Zhen Ding1, Qi Wang2
1Clincal Nutrition Department, Ningbo Medical Center Li Huili Hospital, Ningbo, Zhejiang, 315000, China.
Journal of clinical biochemistry and nutrition
|September 30, 2024
概括
住院COVID-19患者的营养风险和营养不良率很高. 像中性粒细胞与淋巴细胞比率 (NLR) 和控制营养状况评分 (CONUT) 这样的炎症标志物可以预测严重疾病和死亡率.
科学领域:
- 临床营养学 临床营养学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 对于住院COVID-19患者的营养数据有限.
- 营养状况显著影响严重感染患者的结果.
- 早期识别营养风险对于管理COVID-19至关重要.
研究的目的:
- 为了确定住院COVID-19患者营养风险和营养不良的患病率.
- 在这个群体中评估营养干预措施.
- 确定危急状况和死亡率的预测因素.
主要方法:
- 使用得分营养风险查 (NRS 2002),预后营养指数 (PNI) 和控制营养状况得分 (CONUT) 进行营养评估.
- 分析了炎症标志物,包括过敏性C反应蛋白 (hs-CRP),血小板与淋巴细胞的比率 (PLR),中性粒细胞与淋巴细胞的比率 (NLR) 和全身免疫炎症指数 (SII).
- 在464名患者中,使用受体操作特征 (ROC) 曲线分析来评估营养和炎症标志物的预测性表现,以评估危急状况和死亡率.
主要成果:
- 观察到营养风险 (53.00%) 和营养不良 (79.09%由PNI, 88.79%由CONUT) 的高患病率.
- 中性粒细胞与淋巴细胞的比率 (NLR) 和CONUT显示出严重危险状况 (曲线下面面积[AUC] 0.778和0.743) 和死亡率 (AUC 0.814和0.767) 的强有力的预测值.
- hs-CRP,PLR和SII也显示出严重疾病和死亡率的显著预测能力.
结论:
- 住院COVID-19患者表现出营养风险和营养不良的重大负担.
- NLR和CONUT是危急疾病和死亡率的独立预测指标,有助于临床决策.
- 炎症标志物和营养评分是分层 COVID-19 患者风险的宝贵工具.
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
323
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
323
Anorexia Nervosa
48
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
48
Metabolic States of the Body: Fasting and Starvation
1.2K
During the initial hours of fasting, the body uses up its glycogen stores as an energy source. Once these glycogen reserves are depleted, the body begins breaking down stored triglycerides and structural proteins. During this stage, glycerol becomes a key substrate for gluconeogenesis, while free fatty acids undergo beta-oxidation to provide energy for tissues, such as skeletal muscle. In the fasting state, the body spares protein breakdown as much as possible to conserve muscle and structural...
1.2K
Pneumonia III: Complications and Assessment
182
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
182
Urinary Tract Calculi IV: Nutrition therapy and prevention
2
Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
2
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
84
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
84


