六个月的运动干预对老年人糖尿病风险中的白质微观结构的影响
Ryu Lien1, Joyla A Furlano2, Suzanne T Witt3
1School of Kinesiology, Faculty of Health Sciences, Western University, 1151 Richmond Street, London, Ontario, N6A 3K7, Canada.
Cerebral circulation - cognition and behavior
|September 30, 2024
概括
抵抗训练 (RT) 和平衡练习改变了糖尿病风险较高的老年人白质微观结构. 这两种运动类型都会影响大脑网络,但是在不同的区域,这表明对认知和运动功能的有针对性的好处.
科学领域:
- 神经科学是一个神经科学.
- 运动生理学 运动生理学
- 老年学是一门学科.
背景情况:
- 患有糖尿病前期或肥胖的老年人经常经历大脑结构受损.
- 抵抗训练 (RT) 已经显示出在改善不同人群的大脑健康方面的潜力.
- 了解运动对白质的影响对于老年人群的认知健康至关重要.
研究的目的:
- 研究六个月耐力训练 (RT) 计划对糖尿病风险较高的老年人白质微观结构的影响.
- 为了比较RT对大脑结构的影响与平衡和调节训练 (BAT) 控制组.
主要方法:
- 十七名患有糖尿病前期或肥胖的老年人 (平均年龄67.8岁) 被随机分配到RT或BAT半年.
- 使用扩散加权成像 (3T扫描仪) 来评估白质完整性 (FA,MD,RD).
主要成果:
- RT组在认知相关的区域 (如带状回形) 中,平均扩散率 (MD) 和辐射扩散率 (RD) 增加.
- 最佳技术配组表现出多样化的分数异构 (FA) 变化,运动协调区域 (中小脑) 的增加.
- BAT组还显示了运动功能区域 (如内部囊) 的MD和RD下降.
结论:
- 抵抗训练和平衡练习都会导致白质微观结构的变化.
- 观察到的变化发生在不同的大脑区域,可能与每个运动类型的特定需求有关.
- 这些发现突出了不同运动方式对糖尿病风险较高的老年人大脑健康的影响.
相关概念视频
Exercise and Cardiovascular Response
745
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
745
Psychoneuroimmunology: Diabetes and Cancer
25
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
25
Diabetes: Symptoms, Diagnosis, and Complications
515
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
515


