COVID-19对精液脱氧核糖核酸碎片化的暂时影响
Mykola Kvach1, Oleg Nikitin1, Andriy Kost2
1Department of Urology, O.O.Bogomolets National Medical University, Kyiv, Ukraine.
Central European journal of urology
|September 30, 2024
概括
新冠病毒病2019 (COVID-19) 在接种疫苗和未接种疫苗的男性中显著增加了精液DNA碎片化. 这种DNA损伤在康复后两个月达到顶峰,并且在未接种疫苗的个体中需要更长时间才能正常化.
科学领域:
- 生殖医学是一种生殖医学.
- 传染病 传染病 传染病
- 遗传学 是一个遗传学.
背景情况:
- 新型冠状病毒疾病2019 (COVID-19) 影响多个身体系统.
- 最近开发的抗COVID疫苗.
研究的目的:
- 为了调查COVID-19对精液DNA碎片化的影响.
- 为了比较接种疫苗的男性与未接种疫苗的男性的影响.
主要方法:
- 研究包括46名接种疫苗和43名未接种疫苗的男性感染COVID-19.
- 精液DNA碎片化指数 (SDFI) 测量了感染前和每月的恢复后.
- 曼-惠特尼测试用于统计分析 (p <0.05).
主要成果:
- 与基线相比,SDFI在两组中都在COVID-19后显著增加.
- 在康复2个月后,SDFI达到峰值 (40.6%的接种疫苗,49.7%的未接种疫苗).
- 在接种疫苗的男性中SDFI正常化为7个月,在未接种疫苗的男性中为9个月.
结论:
- COVID-19导致精液DNA碎片化的逐渐增加.
- 在未接种疫苗的人群中,这种效果更为明显和持续.
- 疫苗接种可能有助于更快地恢复精液质量参数.
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