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Updated: Jun 11, 2025

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在阿尔茨海默氏病中,TRPC3抑制改善了突触功能障碍和记忆缺陷

Jiaxing Wang, Ling Chen, Zhengjun Wang

    bioRxiv : the preprint server for biology
    |September 30, 2024
    PubMed
    概括

    在阿尔茨海默氏症 (AD) 中,暂时受体潜在的3 (TRPC3) 通道被上调,导致过载和神经毒性. 用JW-65抑制TRPC3通过恢复突触功能为AD提供了一个有希望的治疗策略.

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