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电影唤起的大脑活动和连接性的遗传性

David C Gruskin¹, Daniel J Vieira², Jessica K Lee²

¹Medical Scientist Training Program, Columbia University Irving Medical Center, New York, New York 10032, USA.

bioRxiv : the preprint server for biology

|September 30, 2024

概括

对感官刺激的大脑反应的个体差异具有遗传基础. 这项研究表明,由复杂刺激引起的大脑活动模式是可遗传的,部分原因是神经时间尺度上的遗传影响.

科学领域:

神经科学是一个神经科学.
遗传学是一个遗传学.
认知科学认知科学

背景情况:

个人对感官刺激的体验因大脑反应的差异而有所不同.
神经处理中的这种个体变化的起源在很大程度上是未知的.

研究的目的:

调查感官处理中的个体差异的遗传基础.
量化大脑对复杂刺激的高维度反应的遗传性.
为了确定遗传性是否与较低水平的大脑功能方面有关.

主要方法:

利用来自双胞胎样本的7T功能磁共振成像 (fMRI) 数据.
分析了由电影刺激引起的大脑活动和连接模式.
在空间 ("何处") 与表示 ("如何") 处理中使用过度对齐来区分遗传性.

主要成果:

电影唤起的大脑活动和连接模式是可以在皮层中遗传的.
大脑反应的遗传性可以分解为对空间和表示处理的遗传影响.
神经时间尺度的遗传性部分解释了大脑活动模式的遗传性.

结论:

大脑对复杂的感官刺激的反应表现出显著的遗传性.
遗传因素影响大脑功能的稳定方面,有助于感官处理的个体差异.
神经时间尺度代表了一种遗传的神经机制,它是感官知觉的个体变异的基础.

关键词:

功能磁力共振成像 (fMRI) 是一种功能连接性的功能连接性遗传性遗传性遗传性主体间的相关性.看电影看电影的时间.

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