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Updated: Jun 11, 2025

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来自默克尔细胞癌的巨细胞迁移抑制因子 (MIF) 可能促进慢性淋巴细胞白血病的持续性

Gabriel F Alencar1,2, Haroldo J Rodriguez1,3,4,5, Thomas H Pulliam4

  • 1Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.

bioRxiv : the preprint server for biology
|September 30, 2024
PubMed
概括

默克尔细胞癌 (MCC) 可能促进慢性淋巴细胞白血病 (CLL) 的持续性. 由MCC产生的巨细胞迁移抑制因子 (MIF) 刺激了CLL细胞,这可能解释了MCC治疗后正常化血清.

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Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
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