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相关概念视频

Sympathetic Division of the ANS01:19

Sympathetic Division of the ANS

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The sympathetic division of the autonomic nervous system (ANS) plays a crucial role in preparing the body for stress, physical activity, and increased energy demands. This division activates the "fight-or-flight" response, enabling individuals to respond effectively to challenging situations.
Originating in the thoracic and lumbar spinal cord segments, the preganglionic fibers of the sympathetic division exit the spinal cord through the white ramus communicans. They then enter the...
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Autonomic Nervous System: Overview01:26

Autonomic Nervous System: Overview

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The human nervous system is divided into two main parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS is composed of the brain and spinal cord, while the PNS contains nerve cells, clusters of nerve cells, and the sensory receptors that are outside the CNS. The PNS has two types of nerve cells: sensory (afferent) and motor (efferent). Sensory cells send signals to the CNS from receptors, and motor cells carry signals from the CNS to organs, muscles, and...
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The Sympathetic Nervous System01:25

The Sympathetic Nervous System

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Overview
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Sympathetic Pathways: Sympathetic Chain Ganglia01:21

Sympathetic Pathways: Sympathetic Chain Ganglia

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The sympathetic chain ganglia, also known as the sympathetic trunk ganglia or paravertebral ganglia, are a series of ganglia located bilaterally on either side of the spinal column. These ganglia serve as relay stations for the sympathetic nervous system. Preganglionic neurons originating in the spinal cord project their axons to the sympathetic chain ganglia. Within the ganglia, these preganglionic fibers synapse with postganglionic neurons.
The postganglionic neurons of the sympathetic trunk...
2.3K
Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla01:28

Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla

1.2K
The sympathetic pathways of the collateral ganglia and adrenal medulla serve unique but interconnected roles in the sympathetic response.
Collateral Ganglia
Sympathetic preganglionic axons reach the collateral ganglia along the route of splanchnic nerves. These nerves bypass the sympathetic trunk and communicate with sympathetic postganglionic neurons housed in the prevertebral ganglia. These ganglia supply the organs of the abdominopelvic cavity.
The greater splanchnic nerve, formed by the...
1.2K
Peripheral Nervous System: Ganglia and Nerves01:24

Peripheral Nervous System: Ganglia and Nerves

1.7K
The Peripheral Nervous System (PNS) is a crucial component of the body's neural network, extending beyond the central nervous system (CNS) to bridge the gap between the CNS and the external environment. It encompasses nerves, ganglia, and sensory receptors.
Nerves
The nerve is a bundle of axons that serves as the communication highway in the PNS. Each nerve is ensheathed in a protective layer of connective tissue called the epineurium. This outermost layer safeguards the nerve and supports...
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相关实验视频

Updated: Jun 11, 2025

Efficient Differentiation of Postganglionic Sympathetic Neurons using Human Pluripotent Stem Cells under Feeder-free and Chemically Defined Culture Conditions
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特定器官的交感性内化定义了内脏功能.

Tongtong Wang, Bochuan Teng, Dickson R Yao

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    PubMed
    概括
    此摘要是机器生成的。

    交感神经系统有不同的细胞群,控制着不同的内脏器官功能. 这一发现揭示了自主神经系统对胃肠道,胰腺和胆道的模块化调节.

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    相关实验视频

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    Location, Dissection, and Analysis of the Murine Stellate Ganglion

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    科学领域:

    • 神经科学是一个神经科学.
    • 分子生物学分子生物学
    • 身体生理学 身体生理学

    背景情况:

    • 自主神经系统通过同情和副同情路径调节身体的重要功能.
    • 目前对细胞和分子层面的交感神经系统的理解是有限的.

    研究的目的:

    • 研究腹部交感神经系统的细胞和分子组织.
    • 为了识别在乳-上层介质 (CG-SMG) 中不同的交感神经元群体.

    主要方法:

    • 对CG-SMG的多模转录组分析.
    • 对交感神经元群体的空间映射.
    • 神经扰乱实验用于评估功能角色.

    主要成果:

    • 在CG-SMG中确定了独特的,在空间和分子上可分离的交感种群.
    • 从CG-SMG种群向特定的内脏器官 (胃肠道,胰腺,胆道) 展示了选择性的轴突投射.
    • 显示功能分离,有不同的神经元类调节胃肠道运动与消化和葡萄糖分泌.

    结论:

    • 交感神经系统表现出具有功能分离的神经元群体的分子多样性.
    • 内脏器官功能的模块化调节是通过不同的交感通路实现的.
    • 这项研究为自主控制的细胞和分子基础提供了新的见解.