在环境挑战期间,集体社会行为的神经基础
Tara Raam1, Qin Li1,2, Linfan Gu1,2
1Department of Biological Chemistry and Department of Neurobiology, University of California, Los Angeles, CA, USA.
bioRxiv : the preprint server for biology
|September 30, 2024
概括
寒冷中的老鼠积极和被动地决定聚集在一起. 背中前额叶皮层 (dmPFC) 清楚地编码了这些决定,揭示了集体行为的神经生物学.
科学领域:
- 神经生物学 神经生物学 神经生物学
- 行为生态学 行为生态学
- 计算神经科学是一种神经科学.
背景情况:
- 协调的集体行为对于生存至关重要,但其神经生物学基础尚未得到充分理解.
- 环境挑战,比如寒冷,往往需要群体行为,比如挤在一起进行温度调节.
研究的目的:
- 为了研究神经生物学机制,管理集体行为,以应对热挑战.
- 在小组环境中区分主动与被动社会决策的神经编码.
主要方法:
- 用一组小鼠进行了热挑战测试.
- 采用微内镜成像来监测神经活动.
- 操纵了dorsomedial前额叶皮层 (dmPFC) 的活动,以评估其因果作用.
主要成果:
- 小鼠表现出积极的 (自主发起的) 和被动的 (伴侣发起的) 决定加入或离开群体.
- 在dmPFC中,不同的神经群体编码了主动和被动的聚集决策.
- 沉默dmPFC活动损害了积极的决策,并导致伙伴活动的补偿性增加,保持了小组聚会时间.
结论:
- 背中介前额叶皮质在集体行为背景下调解个人决策方面发挥着至关重要的作用.
- 在dmPFC中的神经生物学机制允许灵活地调整社会行为以满足同居需要.
- 这项研究提供了关于自我组织和协调行动的神经基础的见解,以应对环境压力.
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