VO2MAX,6分钟的步行和肌肉力量都与美国退伍军人的虚弱相关
Kenneth Ladd Seldeen1,2, Ayesha Saqebur Rahman3, Yonas Redae4
1Division of Geriatrics, Department of Internal Medicine and Landon Center on Aging, University at Kansas Medical Center, Kansas City, KS, United States.
Frontiers in physiology
|September 30, 2024
概括
心肺健康和手臂强度与老年退伍军人的虚弱有关. 虽然6分钟步行测试显示出希望,但需要进一步的研究来确认其检测脆弱性的敏感性.
科学领域:
- 老年学和老年医学是老年学和老年医学.
- 心血管呼吸系统生理学
- 物理性能测量测量 物理性能测量
背景情况:
- 脆弱性增加了对不良健康结果的脆弱性,特别是在风险较高的退伍军人中.
- 早期发现脆弱性对于及时的医疗干预和改善患者管理至关重要.
- 了解导致退伍军人虚弱的生理因素,可以为有针对性的预防和治疗策略提供信息.
研究的目的:
- 为了研究老年退伍军人的身体脆弱的生理基础.
- 为了检查心肺呼吸能力 (VO2max),体力表现 (6分钟步行,力量) 和脆弱性之间的关系.
- 评估炎症生物标志物在退伍军人脆弱的表现中的作用.
主要方法:
- 从布法罗退伍军人医疗中心招募了42名60-85岁的退伍军人.
- 使用脆性表型,SPPB和QOL评估脆弱性.
- 测量VO2max,6分钟的步行距离,手臂/腿的力量,以及炎症生物标志物 (CRP,IL-6,IL-10,IFN-γ,TNF-α).
主要成果:
- VO2max与脆弱性得分负相关,与SPPB和QOL正相关.
- 6分钟步行测试与VO2max和SPPB相关,但与脆弱性没有显著关系.
- 手臂强度与虚弱有负相关性,但其与其他性能指标的关系尚不清楚. 在脆弱性组之间,炎症标志物没有显著差异.
结论:
- 对心肺健康的客观测量与老年退伍军人的身体表现,生活质量和脆弱性有关.
- 6分钟步行测试显示了潜力,但需要进一步验证以评估脆弱性.
- 手臂强度可能是脆弱的重要指标,尽管其更广泛的关联需要进一步调查.
相关概念视频
Pulmonary Function Tests
311
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
311
Lung Capacity
49.8K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
49.8K
Exercise and Muscle Performance
1.4K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
1.4K
Muscle Recovery and Fatigue
2.0K
Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective...
2.0K
Spearman's Rank Correlation Test
701
Spearman's rank correlation test, also known as Spearman's rho, is a nonparametric method for assessing the strength and direction of association between two variables. This test is particularly valuable when the data distribution is unknown or when the assumption of normality does not hold. Named after the English psychologist and statistician Dr. Charles Edward Spearman, it serves as the nonparametric counterpart to Pearson's correlation coefficient.
Spearman's test calculates...
Spearman's test calculates...
701
Classification of Skeletal Muscle Fibers
56.1K
Skeletal muscles continuously produce ATP to provide the energy that enables muscle contractions. Skeletal muscle fibers can be categorized into three types based on differences in their contraction speed and how they produce ATP, as well as physical differences related to these factors. Most human muscles contain all three muscle fiber types, albeit in varying proportions.
Slow-Twitch Muscle Fibers
Slow oxidative, muscle fibers appear red due to large numbers of capillaries and high levels of...
Slow-Twitch Muscle Fibers
Slow oxidative, muscle fibers appear red due to large numbers of capillaries and high levels of...
56.1K


