康复培训对帕金森病主观认知衰退认知功能的影响
Shirong Wen1, Guang Yang2, Sijia Xu3
1Department of Neurology, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, People's Republic of China.
Neuropsychiatric disease and treatment
|September 30, 2024
概括
患有主观认知衰退 (PD-SCD+) 的帕金森病患者表现出更快的认知衰退. 康复培训改善了所有PD患者的认知和语言技能,特别是PD-SCD+患者.
科学领域:
- 神经学 神经学
- 认知科学 认知科学
背景情况:
- 帕金森病 (PD) 是一种影响运动功能的神经退行性疾病,通常伴有认知障碍.
- 在PD (PD-SCD+) 中的主观认知衰退 (SCD) 可能表明认知恶化的风险更高.
- 了解PD-SCD+进展和干预措施的有效性对于患者管理至关重要.
研究的目的:
- 在帕金森病 (PD) 中表征主观认知衰退 (SCD) 和其进展.
- 评估康复培训计划对PD患者认知功能的影响.
主要方法:
- 42名PD患者被评估并分为PD-SCD+ (n=22) 和PD-SCD- (n=20) 组.
- 认知评估在3年后重复进行,并在6个月的康复计划后再次进行.
主要成果:
- 与PD-SCD-患者相比,PD-SCD+患者的认知功能 (BJ-MoCA,语义流) 年度下降更为明显.
- 低MMSE,高HAMD,男性性别和SCD的存在与语言技能的下降有关.
- 这两组在康复后的BJ-MoCA得分都有所改善,PD-SCD+显示出明显的语言技能提升.
结论:
- 在PD-SCD+个体中,PD进展与更大的认知衰退有关.
- 语义流是PD认知衰退的关键指标.
- 康复培训在改善PD患者的认知领域和语言技能方面是有效的,特别是在PD-SCD+患者中.
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