心血管疾病患者中认知功能障碍的危险因素
Tunde Pal1,2, Laszlo Barna Iantovics3, Zoltan Preg4,5
1Department of Internal Medicine V, George Emil Palade University of Medicine Pharmacy, Science, and Technology of Targu Mures, Targu Mures, Romania.
Frontiers in public health
|September 30, 2024
概括
心血管疾病患者经常经历认知功能障碍,年龄较大,脏问题和教育程度较低是关键风险因素. 女性性别,心房动和中风增加了高级认知衰退的风险.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 老年学是一门学科.
背景情况:
- 心血管疾病 (CVD) 显著影响认知功能,需要对相关风险因素进行研究.
- 了解心血管疾病,病,人口因素和抑郁症状之间的相互作用对于认知健康至关重要.
- 认知障碍是患有慢性健康状况的老年人群日益关注的问题.
研究的目的:
- 调查与认知功能有关的人口变量,心血管疾病,脏疾病和抑郁症状之间的关系.
- 确定导致已确定的心血管疾病患者认知功能障碍的特定风险因素.
- 在心血管疾病患者队列中使用蒙特利尔认知评估 (MoCA) 分类认知障碍严重程度.
主要方法:
- 一项涉及628名被诊断患有心血管疾病的患者的横截面研究.
- 使用蒙特利尔认知评估 (MoCA) 评估认知功能,将参与者分类为保持认知,轻度认知功能障碍 (CD) 和高级CD组.
- 统计分析包括Cronbach的alpha (Cα) 和麦当劳的omega (Mω) 可靠性,Chi-square,Cramer的V,以及相关性分析以确定关联.
主要成果:
- 轻度认知功能障碍 (CD) 在55.2%的研究队列中普遍存在,平均年龄为67.95岁.
- 在抑郁症状和CD的严重程度之间观察到中度的正相关性 (r=0.25,p<0.0001).
- 在CD和年龄较大 (≥70岁),教育程度较低,吸烟状态,功能障碍 (eGFR 30-59 mL/min/1.73m2),女性性别,心房动和中风史之间发现了显著的关联.
结论:
- 轻度认知功能障碍在患有心血管疾病的患者中很常见.
- 轻度和高级认知功能障碍的危险因素包括年龄较大,教育程度较低,不吸烟状态和功能障碍.
- 先进的认知功能障碍与女性性别,心房的病史和中风特别相关.
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