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适应式轮跟踪,以帮助宽场扫描源光学连贯性断层扫描成像的大型物体,不均的表面拓

Jian Liu¹, Yaping Shi¹, Zhaoyu Gong¹

¹Department of Bioengineering, University of Washington, Seattle, Washington 98105, USA.

Biomedical optics express

|September 30, 2024

概括

这项研究引入了光学连贯断层扫描 (OCT) 的自适应轮跟踪,克服了不均样本的焦点深度限制. 这种方法提高了成像质量,并减少了临床应用的数据.

科学领域:

生物医学光学生物医学光学
医学成像技术医学成像技术

背景情况:

光学连贯断层扫描 (OCT) 面临着灵敏度滚动和有限的焦点深度的挑战.
具有可变表面轮的成像样本在临床环境中加剧了这些限制.

研究的目的:

开发一种适应式的轮跟踪和扫描方法,用于高速,广场的OCT.
克服OCT在具有显著表面变异的成像样本的固有局限性.

主要方法:

集成一个电调节的镜头和可调节的光学延迟线与实时表面轮数据.
预先扫描以创建样本轮图,从而实现定制的扫描协议.
基于光学雷利长度和沿着轮进行短距离成像的深度分辨率分割.

主要成果:

在表面不均的样本中,在视野中保持高对比度和信号噪声比率.
在自适应焦距和延迟线调整中证明有效,以保持一致的成像质量.
与传统的OCT方法相比,获得了较少的数据量.

结论:

适应轮跟踪 OCT 有效地解决了焦点深度和灵敏度滚动问题.
拟议的方法提高了用于临床应用的OCT成像质量和效率.
这一进步对组织结构和血液流动的快速,广场成像充满希望.

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