Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been developed.

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Real-Time SLAM-Based Correction and 3D Visualization for Fluorescence Lifetime Imaging.

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention·2026
Same author

Sleepyhead, deadly awakening: the dynamics of metastatic organotropism, tumor dormancy and therapeutic implications.

Frontiers in oncology·2025
Same author

High-speed wide-field fluorescence lifetime imaging for intraoperative tumor visualization and in vivo multiplexing.

Biomedical optics express·2025
Same author

Optimized laser speckle-based imaging system and methods for deep tissue cerebral blood flow imaging in small rodents.

Neurophotonics·2025
Same author

A comparative study of polydopamine vs. glass ionomer cement for adhesion mechanisms on enamel and dentin using SEM and shear bond strength evaluation.

Scientific reports·2025
Same author

Fluorescence Lifetime Imaging Enables In Vivo Quantification of PD-L1 Expression and Intertumoral Heterogeneity.

Cancer research·2024

相关实验视频

Updated: Jul 4, 2026

Fabrication and Characterization of Optical Tissue Phantoms Containing Macrostructure
10:22

Fabrication and Characterization of Optical Tissue Phantoms Containing Macrostructure

Published on: February 12, 2018

10.6K

可调节的动态组织幻影用于激光光斑成像.

Soumyajit Sarkar1, Murali K1, Hari M Varma1

  • 1Department of Biosciences and Bioengineering, Indian Institute of Technology - Bombay, Mumbai 400076, India.

Biomedical optics express
|September 30, 2024
PubMed
概括
此摘要是机器生成的。

我们开发了一个可调节的动态组织幻影,用于激光光斑血流成像. 这种新的方法使用随机微分方程来准确地复制表面和深层组织的血流动力学.

更多相关视频

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy
09:25

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy

Published on: August 22, 2018

12.4K
Author Spotlight: A Stable Phantom Material for Optical and Acoustic Imaging
04:54

Author Spotlight: A Stable Phantom Material for Optical and Acoustic Imaging

Published on: June 16, 2023

2.8K

相关实验视频

Last Updated: Jul 4, 2026

Fabrication and Characterization of Optical Tissue Phantoms Containing Macrostructure
10:22

Fabrication and Characterization of Optical Tissue Phantoms Containing Macrostructure

Published on: February 12, 2018

10.6K
Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy
09:25

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy

Published on: August 22, 2018

12.4K
Author Spotlight: A Stable Phantom Material for Optical and Acoustic Imaging
04:54

Author Spotlight: A Stable Phantom Material for Optical and Acoustic Imaging

Published on: June 16, 2023

2.8K

科学领域:

  • 生物医学工程 生物医学工程
  • 在光学成像系统中,光学成像
  • 流体动力学 流体动力学

背景情况:

  • 精确模拟血流对于开发和验证非侵入性成像技术至关重要.
  • 基于激光光斑的成像为体内血液流量评估提供了一个有前途的方法.
  • 现有的幻象往往缺乏动态范围和精度,无法完全复制生理条件.

研究的目的:

  • 推出一种新的可调节动态组织幻影,用于基于激光光斑的体内血流成像.
  • 为了证明幻影能够产生模仿生物组织的动态斑点的能力.
  • 为校准和测试激光光斑成像系统提供可靠的工具.

主要方法:

  • 使用随机微分方程 (SDE) 精确控制压电驱动器.
  • 用预定义的概率密度函数和自动相关性生成激光诱导的斑点.
  • 设计一个能够模拟表面和深层组织血流特征的幻影.

主要成果:

  • 开发的幻影成功地产生了具有可控制性质的动态斑点.
  • 斑点图案密切地复制了表面和深层组织血流的特征.
  • 幻影在模拟血流动力学方面表现出相当广泛的范围和准确性.

结论:

  • 这种新型可调节的动态组织幻影对于基于激光光斑的血流成像是有效的.
  • 这种幻影为推进体内血液流量测量技术提供了一个有价值的平台.
  • 经SDE控制的方法提供了一种可靠的方法,用于创建现实的组织流动模拟.