在台湾的青少年中,未经治疗的病与病原性细菌之间的关联
Po-Yen Lin1, Hsin-Yuan Mai1, Ching-Yi Wu2
1Department of Dentistry, College of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Journal of dental sciences
|September 30, 2024
概括
青少年唾液中高水平的Streptococcus mutans (SM) 和Lactobacillus (LB) 与未经治疗的牙损伤的风险增加了一倍. 这项研究强调了监测这些口腔细菌在年轻人群中的重要性.
科学领域:
- 口腔微生物学 口腔微生物学
- 儿科牙科 儿科牙科
- 分子诊断学 分子诊断学
背景情况:
- 青少年使用qPCR的唾液细菌存在有限的研究.
- 突变性链球菌 (SM) 和乳球菌 (LB) 是关键的口腔细菌,与牙损有关.
- 青少年口腔健康需要进一步调查细菌特征.
研究的目的:
- 在台湾青少年的唾液中量化MS和LB.
- 调查唾液SM和LB水平与未经治疗的牙损伤之间的关联.
- 为有针对性的青少年口腔健康干预提供数据.
主要方法:
- 对421名10-18岁的台湾学生进行了横截面研究.
- 使用定量实时聚合酶链反应 (qPCR) 分析的唾液DNA.
- 后勤回归模型用于评估细菌水平与之间的关联.
主要成果:
- 56名青少年 (13.3%) 具有高的SM和LB的综合水平.
- 患有高SM和LB水平的青少年在未经治疗的虫病中,其几率比率为2.05.
- 在高的唾液细菌负载和空存在之间发现了显著的关联.
结论:
- 唾液中MS和LB的水平与青少年未经治疗的牙损伤有显著的关联.
- 在这个人群中,qPCR分析为评估口腔细菌负载提供了有价值的工具.
- 这些发现强调了早期检测和管理口腔细菌的必要性,以预防青少年的.
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