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各种益生菌菌株和Candida物种的聚合和粘附能力:一个体外研究
Panita Chantanawilas1, Nuntiya Pahumunto1,2, Rawee Teanpaisan1,3
1Department of Oral Diagnostic Sciences, Faculty of Dentistry, Prince of Songkla University, Hat Yai, Songkhla, Thailand.
Journal of dental sciences
|September 30, 2024
概括
益生菌抑制了Candida对口腔细胞的粘附,防止了 kandidasis. 它们的聚合和粘附性质是这种抗坎迪达效应的关键,显示了口腔健康应用的潜力.
科学领域:
- 微生物学 微生物学
- 口腔健康 口腔健康
- 益生菌 益生菌 益生菌
背景情况:
- 益生菌抑制*Candida*粘附的能力对于预防殖民和感染至关重要.
- 了解益生菌和*Candida*菌株的特征对于制定有效的口腔健康策略至关重要.
研究的目的:
- 探索益生菌和*Candida*菌株的聚合,粘附和细胞表面特性.
- 评估益生菌及其无细胞超级生物 (CFSs) 作为后生物的疗效,以防止 *Candida* 粘附于人类口腔角质细胞.
主要方法:
- 测试了8种益生菌和5种*Candida*菌株的自身聚合,凝聚和粘附于H357口服角质细胞.
- 评估了益生菌和CFS的细胞表面特性,并研究了益生菌和CFS的抗*Candida*粘附活性.
主要成果:
- 像*Lacticaseibacillus rhamnosus* SD4,*Limosilactobacillus fermentum* SD7和*L. rhamnosus* SD11这样的口服益生菌对H357细胞具有很高的粘附性,与自身聚合,电荷和疏水性有关.
- *Candida albicans* 和 *Candida glabrata* 呈现出显著的粘附性.
- 益生菌及其CFS显著降低了对H357细胞的*Candida*粘附.
结论:
- 口服益生菌菌株具有高聚合性,粘附性和抗*Candida*粘附能力.
- 这些特性表明,口服益生菌对于预防和治疗口腔角膜炎有价值.
- 益生菌及其衍生后生菌在治疗*Candida*感染方面表现有前途.
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