针对自闭症谱系障碍的数字干预:系统性审查和元分析
Tianqi Wang1, Yu Ma1, Xiaonan Du1
1Department of Neurology National Children's Medical Center, Children's Hospital of Fudan University Shanghai China.
Pediatric investigation
|September 30, 2024
概括
数字健康干预措施 (DHIs) 显著改善自闭症谱系障碍 (ASD) 患者的核心症状和智力. 这些发现表明DHIs是有效的,并可能降低ASD患者的医疗费用.
科学领域:
- 数字健康干预措施 数字健康干预措施
- 自闭症谱系障碍研究研究
- 临床试验分析
背景情况:
- 数字健康干预措施 (DHIs) 对自闭症谱系障碍 (ASD) 越来越多,但它们的有效性需要严格的评估.
- 评估DHI的有效性和可行性对于ASD干预的基于证据的实践至关重要.
研究的目的:
- 系统地调查DHI在改善ASD患者的核心症状和智商 (IQ) 的有效性.
- 综合随机临床试验的发现,以确定DHI对ASD结果的影响.
主要方法:
- 在PubMed,Cochrane和Scopus数据库中进行了全面的文献搜索.
- 包括随机临床试验,比较ASD的DHI与对照组 (活跃,等候名单,通常治疗或不治疗).
- 柯克兰偏差风险工具 (RoB2) 用于质量评估.
主要成果:
- 对33项涉及1285名参与者的研究进行分析,发现与对照组相比,与DHI相比,ASD整体表现的改善显著更大 (效果大小=1.89).
- 与等待名单,通常治疗和不治疗对照组相比,DHIs显示出较大的效果大小 (科恩的d:4.27,3.41,4.52).
- 与活性对照组相比,DHIs的效果大小为0.73,表明中等效益.
结论:
- DHI在改善ASD患者的核心症状和智商方面是有效的.
- 这些发现支持使用DHIs作为对ASD有益的干预措施,可能减少与该疾病相关的经济负担.
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