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Updated: Jun 11, 2025

In Vitro Assay to Study Tumor-macrophage Interaction
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Published on: August 1, 2019

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富含铁的巨细胞子集通过Bach1-Ednrb轴促进瘤生长

Ian W Folkert1,2,3,4, William A Molina Arocho2,5, Tsun Ki Jerrick To2,5

  • 1Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.

The Journal of experimental medicine
|September 30, 2024
PubMed
概括

研究人员确定了富含铁的瘤相关巨细胞 (iTAMs),促进瘤生长和免疫抑制. 在iTAM上准内分泌素受体B型 (Ednrb) 和转录因子Bach1对癌症治疗有希望.

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