老年人的伤害性跌倒后痴呆症诊断的风险
Alexander J Ordoobadi1,2,3, Hiba Dhanani2,4, Samir R Tulebaev5
1Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts.
JAMA network open
|September 30, 2024
概括
落显著增加了老年人患阿尔茨海默病和相关痴呆症 (ADRD) 的风险. 与其他伤害相比,在跌倒后的一年内,ADRD新诊断的可能性比其他伤害高21%.
科学领域:
- 老年学是一门学科.
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 轻度认知障碍是阿尔茨海默病和相关痴呆症 (ADRD) 的前体,在老年人中增加了跌倒风险.
- 老年人摔倒后患痴呆症的风险在很大程度上是未知的.
研究的目的:
- 为了确定在老年人下跌后新的ADRD诊断的风险.
主要方法:
- 使用医疗保险服务费用数据 (2014-2015年) 的回顾性队列研究.
- 包括66岁以上的成年人,有创伤 (ED或住院遭遇) 并且没有先前的痴呆症诊断.
- 分析了使用Cox多变量竞争风险模型在1年内新诊断ADRD的危险性.
主要成果:
- 这项研究包括超过240万名老年人;50.1%的老年人经历过跌倒.
- 在10.6%的病例中,在跌倒后1年内诊断出ADRD,而其他损伤的病例为6.1% (P < .001).
- 跌倒独立地与21%的痴呆症诊断风险增加有关 (HR,1.21;P <.001).
结论:
- 在跌倒后,新的ADRD诊断比其他受伤机制更常见.
- 研究结果支持对经历伤害性跌倒的老年人实施认知查,导致急救诊所或住院.
- 早期识别ADRD可以通过降落后认知评估来改善.
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