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从Erythrina senegalensis干皮提取物制成的银纳米颗粒的抗菌和抗氧化研究

Emmanuel Mshelia Halilu¹, Collins Ovenseri Airemwen², Emmanuel Omolan³

¹Faculty of Pharmacy, Cyprus International University, Nicosia, Cyprus/Department of Pharmacognosy and Ethnomedicine, Faculty of Pharmaceutical sciences, Usmanu Danfodiyo University, Sokoto, Nigeria.

Pakistan journal of pharmaceutical sciences

|September 30, 2024

概括

埃里特里娜·塞内加利尼斯 (Erythrina senegalensis) 干皮提取物被用来制造银纳米粒子 (AgNPs). 这些AgNP表现出显著的抗菌和抗氧化特性,归因于黄酸盐的存在.

科学领域:

* 植物化学和纳米技术
* 基于自然产品的纳米材料的探索.

背景情况:

* 传统上使用Erythrina senegalensis治疗微生物感染和糖尿病.
*需要新的抗微生物和抗氧化剂.

研究的目的:

* 用于从Erythrina senegalensis茎树皮提取物中制备银纳米粒子 (AgNPs).
*评估合成的AgNP的抗菌和抗氧化潜力.

主要方法:

* 甲醇茎树皮提取物的植物化学选.
*使用提取物合成AgNP的绿色合成.
* 通过扫描电子显微镜 (SEM) 和X射线衍射 (XRD) 进行AgNP的表征.
*使用DPPH试验评估的抗氧化活性.
* 通过磁盘扩散方法确定抗菌活性.

主要成果:

*植物化学分析证实了素和黄素的存在.
*成功合成和表征了AgNP.
*甲醇提取物和AgNP表现出抗氧化活性,IC50值分别为2.25 mg/mL和3.60 mg/mL.
* 提取物和AgNPs都显示出抗菌作用.

结论:

* 红提取物中的黄类化合物可能会调解AgNP的合成,并赋予生物活性.
*合成的AgNP具有有前途的抗微生物和抗氧化特性.
* 埃里斯蒂娜塞内加拉内斯基衍生的AgNP代表了治疗应用的潜在来源.

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