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Updated: Jun 11, 2025

Time-resolved Förster Resonance Energy Transfer Assays for Measurement of Endogenous Phosphorylated STAT Proteins in Human Cells
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合成的三重体介素-6受体复合体具有STAT3酸化主导的激活特征

Christiane Seibel1, Silke Pudewell1, Puyan Rafii1

  • 1Institute of Biochemistry and Molecular Biology II, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf 40225, Germany.

Cytokine
|September 30, 2024
PubMed
概括

这项研究探讨了嵌合体IL-6受体 (IL-6R) 和gp130蛋白质,揭示了特定结构可以赋予生物活性,并使定制的合成IL-6信号通路成为可能. 这些发现突出了设计新型信号结果的潜力.

关键词:
介质素 6 介质素 6 介质素亚努斯酶是亚努斯酶的一种.gp13030 的使用情况.合成细胞因子生物学

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