探索对瘤学临床试验的认识和认知中的种族差异:从mychoice研究中对基线数据的横截面分析
Ariel Hoadley1, Linda Fleisher2, Cassidy Kenny2
1Department of Social and Behavioral Sciences, Temple University College of Public Health, Philadelphia, PA, United States.
JMIR cancer
|September 30, 2024
概括
黑人/非洲裔美国人瘤病患对临床试验的认识和理解较低,尽管参与的意图相似. 量身定制的教育对于解决他们特定的决策需求和改善试验准入至关重要.
科学领域:
- 在瘤学瘤学.
- 健康差异 在健康上的差异
- 临床试验 临床试验
背景情况:
- 在美国的瘤学临床试验中,黑人/非洲裔美国人成年人仍然代表性不足.
- 减少这种差距的努力取得了有限的成功.
研究的目的:
- 探索黑人/非洲裔美国人瘤病患如何看待临床试验.
- 识别人们对临床试验的看法差异,以加强对临床试验参与决策的支持.
主要方法:
- 在244名成年瘤患者 (黑人/非洲裔美国人与非黑人/非洲裔美国人) 的横截面调查中.
- 评估社会人口结构,临床试验知识,健康素养,感知,患者激活,倡导,自我效能,决策冲突和意图.
- 使用t测试和chi-square测试来比较组.
主要成果:
- 黑人/非洲裔美国人参与者的临床试验知识较低 (P=.006) 和健康素养 (P<.001).
- 他们报告了更大的医疗不信任 (P<.05),对试验益处的认识较低,以及更多的决策不确定性 (P<.05).
- 参与意图在各组之间没有差异.
结论:
- 关于临床试验障碍和益处的信念在黑人/非洲裔美国患者中存在差异,尽管参与意图和对提供者的信任相似.
- 调查结果强调需要量身定制的教育和资源,以满足这一群体的信息和决策需求.
- 提高了解和解决特定问题可以提高黑人/非洲裔美国人瘤病人的临床试验参与.
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