相关实验视频
Updated: Jun 11, 2025
08:03
In Vivo Mouse Model of Spinal Implant Infection
Published on: June 23, 2020
2.3K
用于本地脊椎骨质炎的定义的广泛变化:走在统一诊断框架的道路上,采用超流行病学方法
Francesco Petri1, Omar K Mahmoud2, Said El Zein2
1Division of Public Health, Infectious Diseases and Occupational Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Mayo Clinic, Rochester, 55905, MN, USA; Department of Infectious Diseases, ASST Fatebenefratelli Sacco, "L. Sacco" University Hospital, Milan, 20157, Italy.
The spine journal : official journal of the North American Spine Society
|September 30, 2024
概括
本地脊椎骨髓炎 (NVO) 缺乏标准化的定义,导致各种诊断标准. 在这种日益严重的疾病中,制定统一的框架对于改善患者的治疗结果和推进研究至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 放射学 放射学是一门学科.
- 医疗信息学 医疗信息学
背景情况:
- 原生脊椎骨髓炎 (NVO) 发病率正在上升,但患者的治疗结果仍然很差.
- 现有的临床实践指南刺激了研究,但揭示了NVO的不一致的定义和术语.
- 这种异质性使诊断,治疗和比较研究复杂化.
研究的目的:
- 系统地审查和分析当前文献中原生脊椎骨髓炎 (NVO) 的各种定义.
- 评估这些定义的内容,时间分布和主题聚类.
- 确定用于NVO的诊断标准中的模式和不一致性.
主要方法:
- 一项超流行病学研究,采用对NVO及其同义词的定义的系统审查.
- 从2005年到现在的文献搜索跨越多个数据库,包括试验和队列研究.
- 诊断标准组合的专题综合和分析,使用桑基图可视化.
主要成果:
- 对涉及21,963名患者的171项研究的分析揭示了NVO.诊断标准的92种独特组合.
- 最常见的定义模式包括临床特征与成像,其次是与微生物学结合.
- 定义在很大程度上是由作者生成的,这凸显了缺乏标准化的来源.
结论:
- 这项研究强调了对原生脊椎骨髓炎 (NVO) 标准化诊断标准的迫切需要.
- 建议建立一个协作的Delphi共识,以建立一个统一的诊断框架.
- 标准化,专注于临床特征和MRI,将增强患者护理和研究.
相关概念视频
01:30Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
2
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
2
01:25Endocarditis II: Clinical features and Diagnostic Tests
2
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
2
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
2
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
2
01:25Endocarditis I: Introduction
2
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
2
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
4.1K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.1K
01:26Principles of Disease Surveillance
72
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
72