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Updated: Jun 14, 2025

Characterization of pH-Dependent Reversible Self-Assembly of Amyloid Beta 1-40-Coated Gold Colloids
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Characterization of pH-Dependent Reversible Self-Assembly of Amyloid Beta 1-40-Coated Gold Colloids

Published on: March 21, 2025

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从单个蛋白质中形成可逆或不可逆的粉样纤维的结构性理由

Lukas Frey1, Jiangtao Zhou2, Gea Cereghetti3,4

  • 1Institute of Molecular Physical Science, ETH Zürich, Vladimir-Prelog-Weg 2, Zürich, Switzerland.

Nature communications
|September 30, 2024
PubMed
概括

不可逆转的粉样蛋白形成稳定的跨β结构,需要完整的蛋白质展开. 然而,可逆的粉样蛋白保留了一些原生结构,从而导致较不有序的聚合物.

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