在药物治疗阿片类药物使用障碍中评估移动应用程序对抑郁和焦虑的影响
Michael V Heinz1,2, Damien Lekkas3,4, Veronica Abreu3
1Center for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA. michael.v.heinz@dartmouth.edu.
Npj mental health research
|September 30, 2024
概括
一个移动应用程序有效地减少了阿片类药物使用障碍 (OUD) 患者的抑郁和焦虑,这些患者正在接受OUD (MOUD) 药物治疗. 这种数字干预显示出作为可扩展,具有成本效益的辅助疗法的前景.
科学领域:
- 数字健康干预措施 数字健康干预措施
- 精神病学是一个精神病学.
- 药物中毒药物 药物中毒药物
背景情况:
- 同时出现的抑郁和焦虑在阿片类药物使用障碍 (OUD) 中很常见,但往往治疗不足.
- 标准的OUD治疗可能无法充分解决并发性精神健康状况.
- 治疗OUD (MOUD) 的药物是治疗的基石,但需要辅助疗法.
研究的目的:
- 评估一个移动应用程序的可行性,可接受性和初步有效性,用于治疗接受MOUD的个体的抑郁和焦虑.
- 评估数字干预对抑郁,焦虑和OUD严重性的影响.
- 探索智能手机传感器数字生物标记物的实用性.
主要方法:
- 一个随机对照试验,包括63名OUD成年人接受MOUD和查阳性抑郁/焦虑.
- 参与者被随机分配到为期4周的基于应用程序的干预或通常的治疗.
- 结果包括自我报告的症状严重程度,尿液药物查 (UDS) 和被动智能手机传感器数据.
主要成果:
- 该应用得到了好评 (平均评分为4/5星).
- 与对照组相比,干预组的抑郁症 (d=0.78) 和焦虑症 (d=0.38) 显著减少.
- 两组都改善了OUD严重程度;干预组显示阿片类药物使用率略有下降.
- 被动传感器显示,干预组中社会联系增加.
结论:
- 在接受MOUD的患者中,数字干预对于治疗焦虑和抑郁是可行的和可以接受的.
- 该应用程序显示了作为OUD治疗成本效益高,可扩展的辅助疗法的承诺.
- 需要进一步研究更大的样本大小来证实这些初步发现.
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