相关实验视频

Updated: Jun 11, 2025

Assessment of Selective mRNA Translation in Mammalian Cells by Polysome Profiling
10:00

Assessment of Selective mRNA Translation in Mammalian Cells by Polysome Profiling

Published on: October 28, 2014

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尽管饥饿,但YAP促进了全球mRNA翻译,以推动瘤生长

Daehee Hwang1, Seonguk Baek1, Jeeyoon Chang2

  • 1National Creative Research Initiatives Center for Cell Plasticity, KAIST Stem Cell Center, Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.

Experimental & molecular medicine
|September 30, 2024
PubMed
概括

是的相关蛋白 (YAP) 和TAZ激活蛋白质合成以促进细胞存活和增殖,即使没有营养. 这种涉及mTORC1的机制为治疗YAP/TAZ驱动的癌症提供了新的点.

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