使用口腔表现来诊断儿童的乳病
Aysegul Verim Cicekci1, Aysegul Dogan Demir2, Meltem Bakkal3
1Department of Pediatric Dentistry, Bezmialem Vakif University, Vatan Cad, Istanbul, 34093, Turkey.
BMC gastroenterology
|September 30, 2024
概括
在患有口腔症状的儿童中,可以诊断出腹腔疾病 (CD),例如复发性口腔口腔炎 (RAS) 和摩尔切口体低矿化 (MIH). 牙医应该考虑在这些牙科问题出现的儿童中使用CD.
科学领域:
- 儿科牙科 儿科牙科
- 胃肠病学 胃肠病学
- 遗传学 是一个遗传学.
背景情况:
- 结核病 (CD) 通常没有典型的胃肠道症状,导致诊断不足.
- 口腔表现,包括复发性口腔口腔炎 (RAS) 和状切口体低矿化 (MIH),可以是CD的指标.
研究的目的:
- 调查口腔表现 (RAS和MIH) 在诊断儿童乳病的有用性.
- 评估患有特定口腔疾病的儿童中CD的患病率.
主要方法:
- 评估了60名患有RAS的儿童;40名患有MIH (MIH组),20名没有 (对照组).
- 牙科检查之后进行了关于CD一般症状和诊断测试的问卷:血清学 (tTG-IgA,EMA,总IgA) 和遗传学 (HLA-DQ2,HLA-DQ8).
主要成果:
- 两组之间没有发现显著的统计差异 (p < 0.05).
- 在MIH组中,6名儿童显示tTG-IgA结果异常;其中2名,也对EMA和HLA呈阳性,通过活检诊断出CD.
- 这代表MIH集团的5%.
结论:
- 在呈现RAS的儿童中,特别是那些患有MIH的儿童中,得到了乳病诊断.
- CD与口腔表现的可能性增加有关,如RAS和发育性膜缺陷 (DEDs).
- 牙医应该考虑在RAS和DEDs/MIH患者中使用CD,即使没有其他全身症状.
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