成年人的支气管切除症的患病率:一个元分析
Lu Wang1,2,3,4, Jiajia Wang5,6,7,8, Guixiang Zhao1,2,3,4
1Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-Constructed by Henan Province & Education Ministry of P.R. China, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou, 450046, People's Republic of China.
BMC public health
|September 30, 2024
概括
支气管切除症不是一种罕见的疾病,在全球范围内,每10万成年人中有680人受到影响. 这一元分析突出了其显著的流行率和需要增加研究关注的需要.
科学领域:
- 肺部病理学 肺部病理学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 以前被认为是罕见的支气管切除症,由于患病率和医疗负担的增加,正在引起全球关注.
- 目前尚缺少成人支气管切除症的准确患病率数据,因此需要进行严格的流行病学研究.
- 了解全球流行率对于资源分配和未来的研究方向至关重要.
研究的目的:
- 进行元分析以估计成年人群中支气管切除症的全球患病率.
- 为未来的流行病学研究和支气管病的临床管理提供可靠的参考点.
- 识别不同地理区域和不同人口群体中患病率的潜在变化.
主要方法:
- 在主要数据库 (PubMed,Embase,Cochrane Library,Web of Science) 进行了全面的系统搜索,截至2024年5月31日.
- 数据提取和偏差风险评估由两位作者使用标准化工具独立进行.
- 使用Stata软件进行了元分析,并进行了子组和灵敏度分析,以解决异质性和出版偏差的问题.
主要成果:
- 在15项涵盖超过437万个人的研究中,支气管切除症的综合患病率估计为每10万名成年人中有680人 (95%CI:634-727).
- 患病率因地区而异,韩国 (886/100,000) 和中国 (759/100,000) 的患病率高于美国 (478/100,000).
- 根据吸烟状况和体重指数,人们注意到患病率的显著差异,并且经常观察到16种并发症.
结论:
- 支气管切除症显然不是一种罕见的疾病,挑战其以前的分类.
- 这些发现强调迫切需要增加对支气管病的科学和临床关注.
- 需要进行进一步的研究,以阐明导致其患病率和相关并发症增加的因素.
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