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在小鼠模型中,HPV16突变E6/E7构造具有保护性.

Maryam Moazami Goodarzi1, Ghasem Mosayebi2, Ali Ganji2

  • 1Department of Medical Biotechnology, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran.

BMC biotechnology
|October 1, 2024
PubMed
概括

一种新型的人类乳头瘤病毒16型 (HPV-16) 构造显示出作为治疗疫苗的希望. 在小鼠模型中,再组合蛋白质的输送诱导了比DNA疫苗对HPV-16相关癌症的更强的保护.

关键词:
这种疫苗是DNA疫苗.融合基因是一个融合基因.在HPV-16和HPV-16之间.主要推进战略主要推进战略.再组合蛋白质是一种重组蛋白质.治疗性疫苗是一种治疗性疫苗.瘤特异性抗原 (TSAs) 是指瘤特异性抗原.

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