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上食道关节力学功能与食道运动障碍之间的关系
Juliette Hall1, Milli Gupta2, Michelle Buresi2
1Faculty of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
概括
上食道关节 (UES) 功能障碍与增加的食道动力障碍相关. 即使是轻微的食道问题也与UES功能障碍有关,突出了UES的措施.
科学领域:
- 胃肠病学 胃肠病学
- 生理学 生理学 生理学
- 医疗成像医学成像
背景情况:
- 高分辨率计量 (HRM) 是一种用于诊断食道运动障碍的诊断工具.
- 上食道 (UES) 功能障碍目前还没有被纳入芝加哥食道运动障碍分类系统.
- 芝加哥分类的以前版本引发了关于食道功能障碍可接受程度的争议.
研究的目的:
- 为了研究上胃关节 (UES) 测量和整体胃功能之间的关系.
- 为了确定UES功能障碍是否与食道运动障碍的程度有关.
- 在食道运动障碍的背景下探索UES措施的临床意义.
主要方法:
- 在推中心进行了一项横截面研究.
- 分析了来自2114名患者的高分辨率计量 (HRM) 数据.
- 根据芝加哥分类的不同代定义,患者根据吞失败的数量分为三组.
主要成果:
- 在患者群体中观察到UES平均基础压力,平均残留压力,放松持续时间和恢复时间的显著增加,吞失败的患者数量越来越多.
- 在未能吞的数量和UES平均基础压力,平均残留压力,放松时间和恢复时间之间发现了积极的相关性.
- 这些发现表明食道功能障碍和UES功能参数之间的定量关系.
结论:
- 在患有吞失败的患者中,UES测量有明显的差异.
- 在UES功能障碍和食道动力障碍的严重程度之间存在正相关性.
- 该研究表明,UES措施与食道功能密切相关,即使在轻微的食道功能障碍的情况下也是如此.
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