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Updated: Jun 11, 2025

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斯克里布尔-SGEF-Dlg1复合体调节了上皮细胞中E-cadherin和ZO-1的稳定性,循环和转录

Agustin Rabino1, Sahezeel Awadia1, Nabaa Ali1

  • 1Department of Biological Sciences, University of Toledo, Toledo, OH 43606, USA.

Journal of cell science
|October 1, 2024
PubMed
概括

斯克里布尔-SGEF-Dlg1复合体维持了上皮屏障功能和蛋白质的稳定性. SGEF 枯竭会破坏 E-cadherin 的稳定,从而触发一个反循环,从而减少 E-cadherin 的转录.

关键词:
细胞结点 细胞结点这是E-cadherin.皮质细胞是上皮细胞.对于rhoGEFs来说,这是非常重要的.总体而言,我们的SGEF是SGEF.一个小小的草.

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