自闭症谱系障碍中的胃肠道症状:一种病例对照研究
Khaled Alqoaer1, Maryam O Alenzi2, Doha Abuharfel2
1Pediatric Gastroenterology, King Salman Armed Forces Hospital, Tabuk, SAU.
Cureus
|October 1, 2024
概括
患有自闭症谱系障碍 (ASD) 的儿童经常出现胃肠道 (GI) 症状,如便秘和腹. 诸如自闭症家族史和母亲教育等因素可能会影响这些胃肠道问题.
科学领域:
- 儿科 儿科 儿科
- 胃肠病学 胃肠病学
- 神经发育障碍 神经发育障碍
背景情况:
- 自闭症谱系障碍 (ASD) 是一种复杂的神经发育状况.
- 胃肠道 (GI) 症状在患有ASD的儿童中经常被报告.
- 了解ASD胃肠道问题的患病率和风险因素对于改善生活质量至关重要.
研究的目的:
- 调查ASD儿童的胃肠道症状的频率.
- 在这个人群中确定与胃肠道症状相关的危险因素.
- 为了比较ASD儿童和典型发育 (TD) 儿童之间的GI症状患病率.
主要方法:
- 追溯病例控制研究设计.
- 包括被诊断患有自闭症症的2至14岁儿童 (DSM-5标准) 和匹配的TD对照.
- 通过自己开发的关于人口统计,营养,行为和胃肠道症状的问卷收集数据.
主要成果:
- 在ASD组中,胃肠道症状 (便秘,腹,腹张,未消化的便,口腔) 的患病率显著增加.
- 自闭症组的低收入率更高,纯母乳养率更低.
- 体重异常在ASD组中更常见.
- 家庭有自闭症史和较低的母亲教育与ASD儿童的胃肠道症状有关.
结论:
- 患有自闭症的儿童表现出各种胃肠道症状的高患病率.
- 家庭史上的ASD和母亲的教育水平可能在ASD中 GI症状的表现中发挥作用.
- 需要进一步的研究来探索ASD,胃肠道健康和社会人口因素之间的复杂相互作用.
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