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Updated: Jun 11, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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黄金催化了1,6-enynes和1,6-diynes的高度酶选择性循环添加,由远程键相互作用辅助

Bijin Lin1,2, Ye Xiao1, Tilong Yang3

  • 1Department of Chemistry, State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong 999077, China.

iScience
|October 1, 2024
PubMed
概括

黄金 ((I) 催化剂使得1,6-enynes的高度反选择性 [4+2] 循环添加和1,6-diynes.desymmetric循环添加成为可能. 这些反应产生了复杂的三环化合物,具有出色的立体控制,由联体-基质键驱动.

关键词:
催化剂是一种催化剂.化学 化学 化学

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