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开发针对SARS-CoV-2感染的自组装纳米粒子疫苗的策略

Kaiwen Yang1,2, Youqin Zeng1,2, Xinyu Wu1,2

  • 1College of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Frontiers in immunology
|October 1, 2024
PubMed
概括

自组装的纳米粒子通过改善抗原输送来提高针对SARS-CoV-2的疫苗疗效. 本综述探讨了纳米颗粒疫苗设计的进展以及针对未来的萨尔贝科病毒的通用疫苗的战略.

关键词:
这就是SARS-CoV-2病毒.这就是VLP的VLP.费里丁是一种铁素.自己组装的纳米粒子.疫苗 疫苗 疫苗 疫苗

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Conjugated Proteins

Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...